Assay Detail
Functional
CHEMBL2406156
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Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New bioactive dihydrofuranocoumarins from the roots of the Tunisian Ferula lutea (Poir.) Maire.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.35 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 8.21 |
| CHEMBL1443379 | — | — | 1 | 5.12 |
| CHEMBL51628 | UMBELLIFERONE | — | 1 | 5.09 |
| CHEMBL2402007 | (-)-PRANTSCHIMGIN | — | 1 | 4.83 |
| CHEMBL145 | CAFFEIC ACID | 3.0 | 1 | 4.53 |
| CHEMBL164660 | PSORALEN | 1.0 | 1 | 4.34 |
| CHEMBL416 | METHOXSALEN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 6.13 | nM | 8.21 |
| CHEMBL1443379 | — | IC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL51628 | UMBELLIFERONE | IC50 | = | 8050.0 | nM | 5.09 |
| CHEMBL2402007 | (-)-PRANTSCHIMGIN | IC50 | = | 14950.0 | nM | 4.83 |
| CHEMBL145 | CAFFEIC ACID | IC50 | = | 29730.0 | nM | 4.53 |
| CHEMBL164660 | PSORALEN | IC50 | = | 45600.0 | nM | 4.34 |
| CHEMBL416 | METHOXSALEN | IC50 | > | 100000.0 | nM | - |