Assay Detail
Binding
CHEMBL2406394
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Binding affinity to human LXRalpha-LBD by surface plasmon resonance
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Cyanidin, a natural flavonoid, is an agonistic ligand for liver X receptor alpha and beta and reduces cellular lipid accumulation in macrophages and hepatocytes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 2 | - | - |
| Kd | 2 | 6.35 | 7.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL62136 | T091317 | — | 1 | 7.03 |
| CHEMBL404515 | CYANIDIN | — | 1 | 5.66 |
| CHEMBL2403487 | PHLOROGLUCINALDEHYDE | — | 1 | - |
| CHEMBL37537 | PROTOCATECHUIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL62136 | T091317 | Kd | = | 92.4 | nM | 7.03 |
| CHEMBL404515 | CYANIDIN | Kd | = | 2200.0 | nM | 5.66 |
| CHEMBL2403487 | PHLOROGLUCINALDEHYDE | Activity | - | — | - | |
| CHEMBL37537 | PROTOCATECHUIC ACID | Activity | - | — | - |