Assay Detail
Binding
CHEMBL2409979
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Competitive inhibition of rabbit muscle glycogen phosphorylase b
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Tissue | Muscle tissue |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glycogen phosphorylase, muscle form (CHEMBL4696) ↗| Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
Publication
C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 4.98 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2408225 | — | — | 1 | 6.39 |
| CHEMBL2408224 | — | — | 1 | 5.16 |
| CHEMBL602684 | — | — | 1 | 4.75 |
| CHEMBL3351143 | — | — | 1 | 4.50 |
| CHEMBL3351140 | — | — | 1 | 4.09 |
| CHEMBL2408223 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2408225 | — | Ki | = | 410.0 | nM | 6.39 |
| CHEMBL2408224 | — | Ki | = | 7000.0 | nM | 5.16 |
| CHEMBL602684 | — | Ki | = | 18000.0 | nM | 4.75 |
| CHEMBL3351143 | — | Ki | = | 32000.0 | nM | 4.50 |
| CHEMBL3351140 | — | Ki | = | 81000.0 | nM | 4.09 |
| CHEMBL2408223 | — | Ki | = | 105000.0 | nM | - |