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Assay Detail

CHEMBL2409980

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rabbit muscle glycogen phosphorylase b
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glycogen phosphorylase, muscle form (CHEMBL4696)
Type SINGLE PROTEIN
Organism Oryctolagus cuniculus

Publication

C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase.
Bokor E, Docsa T, Gergely P, Somsák L.
ACS Med Chem Lett (2013) 4 : 612 -615
PubMed 24900719 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 5 4.68 5.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL558445 1 5.05
CHEMBL488967 1 5.00
CHEMBL600003 1 4.80
CHEMBL560324 1 4.42
CHEMBL559793 1 4.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL558445 Ki = 9000.0 nM 5.05
CHEMBL488967 Ki = 10000.0 nM 5.00
CHEMBL600003 Ki = 16000.0 nM 4.80
CHEMBL560324 Ki = 38000.0 nM 4.42
CHEMBL559793 Ki = 76000.0 nM 4.12