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Assay Detail

CHEMBL2411682

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human Raji cells after 48 hrs by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Raji
Confidence 1 — Organism
Curated By Autocuration

Target

Raji (CHEMBL614628)
Type CELL-LINE
Organism Homo sapiens

Publication

Bioactive constituents of Indigofera spicata.
Bueno Pérez L, Li J, Lantvit DD, Pan L, Ninh TN, Chai HB, Soejarto DD, Swanson SM, Lucas DM, Kinghorn AD.
J Nat Prod (2013) 76 : 1498 -1504
PubMed 23895019 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.32 5.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL429023 ROTENONE 1 5.38
CHEMBL240545 ROTENOLONE 1 5.25
CHEMBL241806 TEPHROSIN 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL429023 ROTENONE IC50 = 4200.0 nM 5.38
CHEMBL240545 ROTENOLONE IC50 = 5600.0 nM 5.25
CHEMBL241806 TEPHROSIN IC50 > 10000.0 nM -