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Assay Detail

CHEMBL2411906

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of UCH-L1 in human Z138 cells after 1 hr by immunoblotting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type Z138
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Ubiquitin carboxyl-terminal hydrolase isozyme L1 (CHEMBL6159)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Vialinin A is a ubiquitin-specific peptidase inhibitor.
Okada K, Ye YQ, Taniguchi K, Yoshida A, Akiyama T, Yoshioka Y, Onose J, Koshino H, Takahashi S, Yajima A, Abe N, Yajima S.
Bioorg Med Chem Lett (2013) 23 : 4328 -4331
PubMed 23791076 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1923233 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1923233 IC50 = 3000.0 nM 5.52