Ubiquitin carboxyl-terminal hydrolase isozyme L1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P09936. Use UniProt P09936 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P09936 as the stable identity anchor, then attach disease evidence before program review.
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Review this target as Ubiquitin carboxyl-terminal hydrolase isozyme L1, mapped to UniProt P09936. Sequence length is 223 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ubiquitin carboxyl-terminal hydrolase isozyme L1 as ChEMBL target CHEMBL6159, mapped to UniProt P09936. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P09936 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
| UniProt Accession | P09936 |
| Component Type | Protein |
| Sequence Length | 223 aa |
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Review this target as Ubiquitin carboxyl-terminal hydrolase isozyme L1, mapped to UniProt P09936. Sequence length is 223 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5589657 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL5653589 | 6.97 | Kd | 106.08 | Preclinical |
| CHEMBL4802050 | 6.64 | IC50 | 230.0 | Preclinical |
| CHEMBL5191704 | 6.64 | IC50 | 230.0 | Preclinical |
| CHEMBL3407553 | 6.4 | Ki | 400.0 | Preclinical |
| CHEMBL4791650 | 6.26 | IC50 | 550.0 | Preclinical |
| CHEMBL5169766 | 6.26 | IC50 | 550.0 | Preclinical |
| CHEMBL5763097 | 6.26 | IC50 | 550.0 | Preclinical |
| CHEMBL5770951 | 6.26 | IC50 | 550.0 | Preclinical |
| CHEMBL5772195 | 6.26 | IC50 | 550.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 38 | 155 | 5.3 |
| cell-based format | 18 | 10 | 5.8 |
| assay format | 5 | 5 | 5.3 |
| subcellular format | 3 | 0 | — |