Assay Detail
Functional
CHEMBL2412657
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Hepatitis C virus infected in human Huh7ET cells after 72 hrs by luciferase reporter gene assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cyclophilin inhibitors as antiviral agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.90 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2407585 | — | — | 1 | 7.40 |
| CHEMBL1269597 | SCY 635 | 2.0 | 1 | 6.91 |
| CHEMBL2407588 | — | — | 1 | 6.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2407585 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL1269597 | SCY 635 | EC50 | = | 122.0 | nM | 6.91 |
| CHEMBL2407588 | — | EC50 | = | 410.0 | nM | 6.39 |