Assay Detail
Binding
CHEMBL2415805
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of soybean lipoxygenase-1 assessed as inhibition of conversion of linoleic acid into hydroperoxy eicosatetraenoic acid preincubated for 10 mins before substrate addition measured over 20 mins by spectrophotometric assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Glycine max |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Catalytic asymmetric total synthesis of (S)-(-)-zearalenone, a novel lipoxygenase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.29 | 4.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL454173 | ZEARALENONE | — | 1 | 4.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL454173 | ZEARALENONE | IC50 | = | 51000.0 | nM | 4.29 |