Assay Detail
Functional
CHEMBL2416155
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Cytotoxicity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SH-SY5Y |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and tubulin-binding properties of non-symmetrical click C5-curcuminoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.04 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2413471 | — | — | 1 | 5.40 |
| CHEMBL2413475 | — | — | 1 | 4.97 |
| CHEMBL2413469 | — | — | 1 | 4.97 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.94 |
| CHEMBL2413474 | — | — | 1 | 4.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2413471 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL2413475 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL2413469 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL140 | CURCUMIN | IC50 | = | 11400.0 | nM | 4.94 |
| CHEMBL2413474 | — | IC50 | = | 11800.0 | nM | 4.93 |