Assay Detail
Binding
CHEMBL2417341
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Reversible inhibition of human recombinant FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated for 20 mins before substrate addition by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.81 | 7.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL177577 | — | — | 1 | 7.48 |
| CHEMBL2413160 | — | — | 1 | 4.99 |
| CHEMBL2415105 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL177577 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL2413160 | — | IC50 | = | 10300.0 | nM | 4.99 |
| CHEMBL2415105 | — | IC50 | = | 11000.0 | nM | 4.96 |