Assay Detail
Functional
CHEMBL2422693
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Antioxidant activity assessed as NADH/phenazine methosulfate generated superoxide anion scavenging after 2 mins by NBT reduction assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Prenylated and geranylated flavonoids increase production of reactive oxygen species in mouse macrophages but inhibit the inflammatory response.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.26 | 4.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223256 | NYMPHAEOL A | — | 1 | 4.38 |
| CHEMBL393136 | POMIFERIN | — | 1 | 4.13 |
| CHEMBL238188 | OSAJIN | — | 1 | - |
| CHEMBL221907 | CUDRAFLAVONE B | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223256 | NYMPHAEOL A | IC50 | = | 41200.0 | nM | 4.38 |
| CHEMBL393136 | POMIFERIN | IC50 | = | 73300.0 | nM | 4.13 |
| CHEMBL238188 | OSAJIN | IC50 | > | 1000000.0 | nM | - |
| CHEMBL221907 | CUDRAFLAVONE B | IC50 | = | 219000.0 | nM | - |