Assay Detail
Functional
CHEMBL2422882
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against wild type HIV1 3B infected in human MT4 cells assessed as protection against virus-induced effect
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 9.22 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL71728 | — | — | 1 | 9.52 |
| CHEMBL70663 | DAPIVIRINE | 3.0 | 1 | 8.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL71728 | — | EC50 | = | 0.3 | nM | 9.52 |
| CHEMBL70663 | DAPIVIRINE | EC50 | = | 1.2 | nM | 8.92 |