Assay Detail
Binding
CHEMBL2428205
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to androgen receptor (unknown origin) by fluorescence polarization assay
5
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of potent and selective nonsteroidal indazolyl amide glucocorticoid receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.11 | 6.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2426624 | — | — | 2 | 6.61 |
| CHEMBL2426636 | — | — | 1 | 5.60 |
| CHEMBL2426663 | — | — | 1 | - |
| CHEMBL2426662 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2426624 | — | Ki | = | 243.0 | nM | 6.61 |
| CHEMBL2426636 | — | Ki | = | 2513.0 | nM | 5.60 |
| CHEMBL2426624 | — | Ki | > | 4166.0 | nM | - |
| CHEMBL2426663 | — | Ki | > | 25000.0 | nM | - |
| CHEMBL2426662 | — | Ki | > | 25000.0 | nM | - |