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Assay Detail

CHEMBL2428517

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV1 LAV
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Highly potent HIV-1 protease inhibitors with novel tricyclic P2 ligands: design, synthesis, and protein-ligand X-ray studies.
Ghosh AK, Parham GL, Martyr CD, Nyalapatla PR, Osswald HL, Agniswamy J, Wang YF, Amano M, Weber IT, Mitsuya H.
J Med Chem (2013) 56 : 6792 -6802
PubMed 23947685 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.74 8.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1232930 1 8.74

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1232930 IC50 = 1.8 nM 8.74