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Assay Detail

CHEMBL2428529

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Partial antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-stimulated Ca2+ uptake
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

The carbonate analogues of 5'-halogenated resiniferatoxin as TRPV1 ligands.
Lim KS, Lee H, Kim SE, Ha TH, Ann J, Son K, Choi S, Sun W, Pearce LV, DeAndrea-Lazarus IA, Blumberg PM, Lee J.
Eur J Med Chem (2013) 68 : 233 -243
PubMed 23981530 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.58 7.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2425549 1 7.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2425549 Ki = 26.2 nM 7.58