Assay Detail
Binding
CHEMBL2429068
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to L3MBTL3 (unknown origin) by isothermal titration calorimetric assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Lethal(3)malignant brain tumor-like protein 3 (CHEMBL1287623) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 6.53 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2426364 | — | — | 1 | 6.92 |
| CHEMBL2424677 | — | — | 1 | 6.46 |
| CHEMBL2426498 | — | — | 1 | 6.41 |
| CHEMBL2426375 | — | — | 1 | 6.33 |
| CHEMBL2426376 | — | — | 1 | - |
| CHEMBL2426374 | — | — | 1 | - |
| CHEMBL2426373 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2426364 | — | Kd | = | 120.0 | nM | 6.92 |
| CHEMBL2424677 | — | Kd | = | 350.0 | nM | 6.46 |
| CHEMBL2426498 | — | Kd | = | 390.0 | nM | 6.41 |
| CHEMBL2426375 | — | Kd | = | 470.0 | nM | 6.33 |
| CHEMBL2426376 | — | Kd | - | — | - | |
| CHEMBL2426374 | — | Kd | - | — | - | |
| CHEMBL2426373 | — | Kd | - | — | - |