Lethal(3)malignant brain tumor-like protein 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q96JM7. Use UniProt Q96JM7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96JM7 as the stable identity anchor, then attach disease evidence before program review.
Lethal(3)malignant brain tumor-like protein 3
Review this target as Lethal(3)malignant brain tumor-like protein 3, mapped to UniProt Q96JM7. Sequence length is 780 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Lethal(3)malignant brain tumor-like protein 3 as ChEMBL target CHEMBL1287623, mapped to UniProt Q96JM7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Lethal(3)malignant brain tumor-like protein 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q96JM7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lethal(3)malignant brain tumor-like protein 3 |
| UniProt Accession | Q96JM7 |
| Component Type | Protein |
| Sequence Length | 780 aa |
Lethal(3)malignant brain tumor-like protein 3
Review this target as Lethal(3)malignant brain tumor-like protein 3, mapped to UniProt Q96JM7. Sequence length is 780 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2426364 | 7.62 | IC50 | 24.0 | Preclinical |
| CHEMBL3134130 | 7.43 | IC50 | 37.0 | Preclinical |
| CHEMBL2426365 | 7.41 | IC50 | 39.0 | Preclinical |
| CHEMBL2426360 | 7.37 | IC50 | 43.0 | Preclinical |
| CHEMBL2426366 | 7.32 | IC50 | 48.0 | Preclinical |
| CHEMBL2426498 | 7.32 | IC50 | 48.0 | Preclinical |
| CHEMBL3134144 | 7.32 | IC50 | 48.0 | Preclinical |
| CHEMBL2426367 | 7.28 | IC50 | 53.0 | Preclinical |
| CHEMBL3134146 | 7.23 | IC50 | 59.0 | Preclinical |
| CHEMBL2424678 | 7.21 | IC50 | 61.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 35 | 102 | 6.3 |
| cell-based format | 13 | 1 | 6.8 |
| subcellular format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 6.3 |