Assay Detail
Functional
CHEMBL2429567
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Cytotoxicity against human HeLa cells assessed as cell survival after 24 hrs by trypan blue exclusion assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthetic polyamines activating autophagy: effects on cancer cell death.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.08 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2398522 | — | — | 1 | 5.80 |
| CHEMBL55568 | — | — | 1 | 4.75 |
| CHEMBL55587 | — | — | 1 | 4.68 |
| CHEMBL27673 | METHOCTRAMINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2398522 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL55568 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL55587 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL27673 | METHOCTRAMINE | IC50 | > | 100000.0 | nM | - |