Assay Detail
ADMET
CHEMBL2432652
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against KM mouse splenic lymphocytes
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | Splenic lymphocyte |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
C23 steroids from the venom of Bufo bufo gargarizans.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.10 | 4.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2431150 | — | — | 1 | 4.10 |
| CHEMBL250172 | BUFOGENIN | 2.0 | 1 | - |
| CHEMBL2431149 | — | — | 1 | - |
| CHEMBL2431148 | — | — | 1 | - |
| CHEMBL2431147 | — | — | 1 | - |
| CHEMBL2429881 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2431150 | — | IC50 | = | 79400.0 | nM | 4.10 |
| CHEMBL250172 | BUFOGENIN | IC50 | > | 100000.0 | nM | - |
| CHEMBL2431149 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2431148 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2431147 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2429881 | — | IC50 | > | 100000.0 | nM | - |