Assay Detail
Binding
CHEMBL2432950
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Inhibition of human p38alpha MAPK in presence of 50 uM ATP
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A Casein kinase 1/Checkpoint kinase 1 pyrazolo-pyridine protein kinase inhibitor as novel activator of the p53 pathway.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.54 | 5.69 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2430324 | — | — | 1 | 5.69 |
| CHEMBL410456 | — | — | 1 | 5.38 |
| CHEMBL2430323 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2430324 | — | IC50 | = | 2042.0 | nM | 5.69 |
| CHEMBL410456 | — | IC50 | = | 4154.0 | nM | 5.38 |
| CHEMBL2430323 | — | IC50 | - | — | - |