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Assay Detail

CHEMBL2439302

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Activation of p53 in human RCC45ConALuc cells after 16 hrs by luciferase reporter gene assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cellular tumor antigen p53 (CHEMBL4096)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Indenoindoles and cyclopentacarbazoles as bioactive compounds: synthesis and biological applications.
Rongved P, Kirsch G, Bouaziz Z, Jose J, Le Borgne M.
Eur J Med Chem (2013) 69 : 465 -479
PubMed 24090918 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.10 7.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2436173 1 7.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2436173 EC50 = 80.0 nM 7.10