Assay Detail
Functional
CHEMBL2439671
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Cytotoxicity against human KB-3-1 cells after 72 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB 3-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New phenstatin-fatty acid conjugates: synthesis and evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.41 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL276625 | PHENSTATIN | — | 1 | 7.82 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 7.75 |
| CHEMBL2435386 | ISOPHENSTATIN | — | 1 | 6.84 |
| CHEMBL2435382 | — | — | 1 | 6.79 |
| CHEMBL2435385 | — | — | 1 | 6.26 |
| CHEMBL2435381 | — | — | 1 | 6.11 |
| CHEMBL2435384 | — | — | 1 | 5.76 |
| CHEMBL2435380 | — | — | 1 | 5.56 |
| CHEMBL2435383 | — | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL276625 | PHENSTATIN | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL107 | COLCHICINE | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL2435386 | ISOPHENSTATIN | IC50 | = | 146.0 | nM | 6.84 |
| CHEMBL2435382 | — | IC50 | = | 163.0 | nM | 6.79 |
| CHEMBL2435385 | — | IC50 | = | 547.0 | nM | 6.26 |
| CHEMBL2435381 | — | IC50 | = | 786.0 | nM | 6.11 |
| CHEMBL2435384 | — | IC50 | = | 1721.0 | nM | 5.76 |
| CHEMBL2435380 | — | IC50 | = | 2777.0 | nM | 5.56 |
| CHEMBL2435383 | — | IC50 | = | 16932.0 | nM | 4.77 |