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Assay Detail

CHEMBL2445167

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human serum ACE
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Angiotensin-converting enzyme (CHEMBL1808)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Perindopril and ramipril phosphonate analogues as a new class of angiotensin converting enzyme inhibitors.
Gomez C, Berteina-Raboin S, De Nanteuil G, Guillaumet G.
Bioorg Med Chem (2013) 21 : 7216 -7221
PubMed 24095015 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.00 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1237 LISINOPRIL ANHYDROUS 4.0 1 10.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1237 LISINOPRIL ANHYDROUS IC50 = 0.1 nM 10.00