Assay Detail
Functional
CHEMBL2445842
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Antioxidant activity assessed as inhibition of H2O2-induced ROS production by DCFH assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Multifunctional cyclic D,L-α-peptide architectures stimulate non-insulin dependent glucose uptake in skeletal muscle cells and protect them against oxidative stress.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.26 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3037933 | — | — | 1 | 6.70 |
| CHEMBL3037934 | — | — | 1 | 6.52 |
| CHEMBL153 | TROLOX | — | 1 | 6.46 |
| CHEMBL3037932 | — | — | 1 | 6.40 |
| CHEMBL17962 | HISTIDINE | 2.0 | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3037933 | — | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL3037934 | — | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL153 | TROLOX | EC50 | = | 350.0 | nM | 6.46 |
| CHEMBL3037932 | — | EC50 | = | 400.0 | nM | 6.40 |
| CHEMBL17962 | HISTIDINE | EC50 | = | 6000.0 | nM | 5.22 |