Assay Detail
Functional
CHEMBL2447114
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Growth inhibition of human LNCaP-FGC cells after 72 hrs by MTS assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LNCaP-Clone-FGC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Potent Vinblastine C20' Ureas Displaying Additionally Improved Activity Against a Vinblastine-Resistant Cancer Cell Line.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 9.49 | 10.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3037931 | — | — | 1 | 10.70 |
| CHEMBL2441610 | — | — | 1 | 9.62 |
| CHEMBL2441607 | — | — | 1 | 9.35 |
| CHEMBL159 | VINBLASTINE | 4.0 | 1 | 8.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3037931 | — | IC50 | = | 0.02 | nM | 10.70 |
| CHEMBL2441610 | — | IC50 | = | 0.24 | nM | 9.62 |
| CHEMBL2441607 | — | IC50 | = | 0.45 | nM | 9.35 |
| CHEMBL159 | VINBLASTINE | IC50 | = | 5.1 | nM | 8.29 |