Assay Detail
Binding
CHEMBL3047385
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Glycine max (soybean) lipoxygenase using sodium linoleate as substrate
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Glycine max |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The novel amidocarbamate derivatives of ketoprofen: synthesis and biological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.32 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1172493 | — | — | 1 | 4.68 |
| CHEMBL1170394 | — | — | 1 | 4.50 |
| CHEMBL1172092 | — | — | 1 | 4.07 |
| CHEMBL1170146 | — | — | 1 | 4.02 |
| CHEMBL571 | KETOPROFEN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1172493 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL1170394 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL1172092 | — | IC50 | = | 86000.0 | nM | 4.07 |
| CHEMBL1170146 | — | IC50 | = | 95000.0 | nM | 4.02 |
| CHEMBL571 | KETOPROFEN | IC50 | = | 130000.0 | nM | - |