Assay Detail
Functional
CHEMBL3053144
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Sindbis virus infected Hela cells assessed as inhibition of virus-induced cytopathicity
15
Total Activities
15
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Sindbis virus |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The novel amidocarbamate derivatives of ketoprofen: synthesis and biological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 14 | - | - |
| EC50 | 1 | 4.96 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1170394 | — | — | 1 | 4.96 |
| CHEMBL153 | TROLOX | — | 1 | - |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | — | 1 | - |
| CHEMBL145 | CAFFEIC ACID | 3.0 | 1 | - |
| CHEMBL571 | KETOPROFEN | 4.0 | 1 | - |
| CHEMBL1172546 | — | — | 1 | - |
| CHEMBL1171686 | — | — | 1 | - |
| CHEMBL1170395 | — | — | 1 | - |
| CHEMBL1170146 | — | — | 1 | - |
| CHEMBL1172093 | — | — | 1 | - |
| CHEMBL1172092 | — | — | 1 | - |
| CHEMBL1172091 | — | — | 1 | - |
| CHEMBL1170348 | — | — | 1 | - |
| CHEMBL1170347 | — | — | 1 | - |
| CHEMBL1172493 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1170394 | — | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL153 | TROLOX | Activity | - | — | - | |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | Activity | - | — | - | |
| CHEMBL145 | CAFFEIC ACID | Activity | - | — | - | |
| CHEMBL571 | KETOPROFEN | Activity | - | — | - | |
| CHEMBL1172546 | — | Activity | - | — | - | |
| CHEMBL1171686 | — | Activity | - | — | - | |
| CHEMBL1170395 | — | Activity | - | — | - | |
| CHEMBL1170146 | — | Activity | - | — | - | |
| CHEMBL1172093 | — | Activity | - | — | - | |
| CHEMBL1172092 | — | Activity | - | — | - | |
| CHEMBL1172091 | — | Activity | - | — | - | |
| CHEMBL1170348 | — | Activity | - | — | - | |
| CHEMBL1170347 | — | Activity | - | — | - | |
| CHEMBL1172493 | — | Activity | - | — | - |