Assay Detail
Binding
CHEMBL3057572
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Rattus norvegicus (rat) chimeric dopamine D2 trunk/D3 tail receptor transfected in african green monkey COS7 cells after 1 hr by beta scintillation counting
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | COS-7 |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Dopamine receptor D2 and D3 (CHEMBL2111342) ↗| Type | SELECTIVITY GROUP |
| Organism | Rattus norvegicus |
Publication
Heterodimerization of G-Protein-Coupled Receptors Reveals an Unexpected Level of Pharmacological Diversity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Bmax | 1 | - | - |
| Kd | 1 | 10.02 | 10.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20734 | NEMONAPRIDE | 2.0 | 2 | 10.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20734 | NEMONAPRIDE | Kd | = | 0.095 | nM | 10.02 |
| CHEMBL20734 | NEMONAPRIDE | Bmax | = | 159.0 | fmol/mg | - |