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Assay Detail

CHEMBL3061801

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Saccharomyces cerevisiae (baker's yeast) alpha-glucosidase using p-nitrophenyl glucopyranoside as substrate preincubated for 30 min before substrate addition measured after 1 hr by spectrophotometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Saccharomyces cerevisiae
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Alpha-glucosidase MAL62 (CHEMBL4357)
Type SINGLE PROTEIN
Organism Saccharomyces cerevisiae

Publication

Docking study on trametenolic acid B as a -glucosidase inhibitor
Luo H, Wang J, Zhou Y, Zou K
Med Chem Res (2012) 21 : 2141 -2144
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.77 4.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL387689 TRAMETENOLIC ACID 1 4.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL387689 TRAMETENOLIC ACID IC50 = 17090.0 nM 4.77