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Assay Detail

CHEMBL3063346

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antifungal activity against Fusarium graminearum isolate 106 after 8 hr by microscopic analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Fusarium graminearum
Confidence 1 — Organism
Curated By Autocuration

Target

Fusarium graminearum (CHEMBL2366834)
Type ORGANISM
Organism Fusarium graminearum

Publication

Comparison of the declining triazole sensitivity of Gibberella zeae and increased sensitivity achieved by advances in triazole fungicide development
Klix MB, Verreet JA, Beyer M.
Crop Prot (2007) 26 : 683 -690
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 4 4.50 4.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2251446 PROTHIOCONAZOLE 1 4.50
CHEMBL486029 EPOXICONAZOLE 1 -
CHEMBL1883512 METCONAZOLE 1 -
CHEMBL487186 TEBUCONAZOLE 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2251446 PROTHIOCONAZOLE EC50 = 32000.0 nM 4.50
CHEMBL486029 EPOXICONAZOLE EC50 = 10800000.0 nM -
CHEMBL1883512 METCONAZOLE EC50 = 177000.0 nM -
CHEMBL487186 TEBUCONAZOLE EC50 = 327000.0 nM -