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Assay Detail

CHEMBL3068024

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Uncompetitive inhibition of yeast alpha-glucosidase by Lineweaver-Burk plot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Saccharomyces cerevisiae
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Alpha-glucosidase MAL62 (CHEMBL4357)
Type SINGLE PROTEIN
Organism Saccharomyces cerevisiae

Publication

Synthesis and structureactivity relationships of serotonin derivatives effect on -glucosidase inhibition
Takahashi T, Miyazawa M
Med Chem Res (2012) 21 : 1762 -1770
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 4.14 4.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL559089 N-CAFFEOYLSEROTONIN 1 4.19
CHEMBL1760547 N-P-COUMAROYL SEROTONIN 1 4.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL559089 N-CAFFEOYLSEROTONIN Ki = 64400.0 nM 4.19
CHEMBL1760547 N-P-COUMAROYL SEROTONIN Ki = 81600.0 nM 4.09