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Assay Detail

CHEMBL3068698

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Serpentes (snake) venom phosphodiesterase using bis(p-nitrophenyl)phosphate as substrate incubated for 30 min prior to substrate addition by spectrophotometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Serpentes
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

cAMP-specific 3',5'-cyclic phosphodiesterase 4B (CHEMBL2366442)
Type SINGLE PROTEIN
Organism Crotalus adamanteus

Publication

Synthesis and enzyme inhibitory activities of some new pyrazole-based heterocyclic compounds
Harit T, Malek F, Bali BE, Khan A, Dalvandi K, Marasini BP, Noreen S, Malik R, Khan S, Iqbal Choudhary M
Med Chem Res (2012) 21 : 2772 -2778
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.13 4.13

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL858 EDETIC ACID 3.0 1 4.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL858 EDETIC ACID IC50 = 74000.0 nM 4.13