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Assay Detail

CHEMBL3074592

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Binding
Inhibition of xanthine oxidase assessed as conversion of xanthine to uric acid incubated for 3 min
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Bioactive ellagitannins from Cunonia macrophylla, an endemic Cunoniaceae from New Caledonia.
Fogliani B, Raharivelomanana P, Bianchini JP, Bouraïma-Madjèbi S, Hnawia E.
Phytochemistry (2005) 66 : 241 -247
PubMed 15652581 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 8 4.81 5.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1939391 ELLAGIC ACID 4-O-XYLOPYRANOSIDE 1 5.33
CHEMBL6246 ELLAGIC ACID 2.0 1 5.03
CHEMBL50 QUERCETIN 3.0 1 5.00
CHEMBL288114 GALLIC ACID 2.0 1 4.38
CHEMBL525240 CHEBULAGIC ACID 1 4.32
CHEMBL2289445 MALLOREPANIN 1 -
CHEMBL448796 MALLOTINIC ACID 1 -
CHEMBL449392 CORILAGIN 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1939391 ELLAGIC ACID 4-O-XYLOPYRANOSIDE IC50 = 4700.0 nM 5.33
CHEMBL6246 ELLAGIC ACID IC50 = 9300.0 nM 5.03
CHEMBL50 QUERCETIN IC50 = 10000.0 nM 5.00
CHEMBL288114 GALLIC ACID IC50 = 41700.0 nM 4.38
CHEMBL525240 CHEBULAGIC ACID IC50 = 48000.0 nM 4.32
CHEMBL2289445 MALLOREPANIN IC50 > 100000.0 nM -
CHEMBL448796 MALLOTINIC ACID IC50 > 100000.0 nM -
CHEMBL449392 CORILAGIN IC50 > 100000.0 nM -