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Compound Detail

CHEMBL1939391

ELLAGIC ACID 4-O-XYLOPYRANOSIDE
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O=c1oc2c(O)c(O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)cc3c(=O)oc4c(O)c(O)cc1c4c23

Basic Information

ChEMBL ID CHEMBL1939391
Name ELLAGIC ACID 4-O-XYLOPYRANOSIDE
Phase Preclinical
Structure Type MOL
InChI Key KNURQRIPZJJYQO-PJIMMEPBSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

434.3
MW (Da)
-0.58
ALogP
12
HBA
6
HBD
200.3
PSA (Ų)
0.13
QED
2
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C19H14O12
MW 434.31
Aromatic Rings 4
Heavy Atoms 31
NP-Likeness 1.86

Activity Summary

IC50 1 meas. best 5.33

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 5.33 5.33 4700.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked IC50 = 4700.0 nM 5.33 Inhibition of xanthine oxidase assessed as conversion of xanthine to uric acid i... 15652581

Literature References

PubMed DOI Target Context # Activities
22196120 10.1016/j.bmcl.2011.11.109 Unchecked 1
15652581 10.1016/j.phytochem.2004.11.016 Unchecked 1
15652581 10.1016/j.phytochem.2004.11.016 Candida albicans 1
15652581 10.1016/j.phytochem.2004.11.016 Corynebacterium accolens 1
15652581 10.1016/j.phytochem.2004.11.016 Staphylococcus aureus 1
15652581 10.1016/j.phytochem.2004.11.016 Pectobacterium carotovorum 1

Data from ChEMBL 36 via Core Engine