Assay Detail
Functional
CHEMBL3076580
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against Rattus norvegicus (rat) C6 cells assessed as cell viability after 24 hr by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | C6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimicrobial and anticancer effects of some 2-(substitutedsulfanyl)-N-(5-methyl-isoxazol-3-yl)acetamide derivatives
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.17 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1391713 | — | — | 1 | 7.00 |
| CHEMBL1602103 | — | — | 1 | 6.68 |
| CHEMBL2283204 | — | — | 1 | 6.36 |
| CHEMBL2283205 | — | — | 1 | 6.24 |
| CHEMBL1517744 | — | — | 1 | 6.19 |
| CHEMBL2283206 | — | — | 1 | 5.92 |
| CHEMBL1352217 | — | — | 1 | 5.85 |
| CHEMBL2283207 | — | — | 1 | 5.83 |
| CHEMBL1486032 | — | — | 1 | 5.50 |
| CHEMBL1361345 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1391713 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL1602103 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL2283204 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL2283205 | — | IC50 | = | 580.0 | nM | 6.24 |
| CHEMBL1517744 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL2283206 | — | IC50 | = | 1210.0 | nM | 5.92 |
| CHEMBL1352217 | — | IC50 | = | 1410.0 | nM | 5.85 |
| CHEMBL2283207 | — | IC50 | = | 1470.0 | nM | 5.83 |
| CHEMBL1486032 | — | IC50 | = | 3190.0 | nM | 5.50 |
| CHEMBL1361345 | — | IC50 | - | — | - |