Assay Detail
Functional
CHEMBL3081208
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Phytotoxicity against Scenedesmus acutus assessed as inhibition of chlorophyll content after 48 hr under dark conditions by spectrophotometry relative to untreated control
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Scenedesmus acutus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of 1, 2, 4-Triazolo[1, 5-a]-1, 3, 5-triazine Derivatives for Phytotoxic Activity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.19 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2272807 | — | — | 1 | 7.82 |
| CHEMBL1871400 | OXYFLUORFEN | — | 1 | 7.40 |
| CHEMBL2269745 | CHLOROPHTHALIUM | — | 1 | 7.10 |
| CHEMBL2272809 | — | — | 1 | 4.85 |
| CHEMBL2272819 | — | — | 1 | 4.42 |
| CHEMBL2272818 | — | — | 1 | 4.30 |
| CHEMBL2272808 | — | — | 1 | 4.00 |
| CHEMBL2272811 | — | — | 1 | 4.00 |
| CHEMBL2272810 | — | — | 1 | 4.00 |
| CHEMBL2272812 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2272807 | — | IC50 | = | 15.14 | nM | 7.82 |
| CHEMBL1871400 | OXYFLUORFEN | IC50 | = | 39.81 | nM | 7.40 |
| CHEMBL2269745 | CHLOROPHTHALIUM | IC50 | = | 79.43 | nM | 7.10 |
| CHEMBL2272809 | — | IC50 | = | 14125.38 | nM | 4.85 |
| CHEMBL2272819 | — | IC50 | = | 38018.94 | nM | 4.42 |
| CHEMBL2272818 | — | IC50 | = | 50118.72 | nM | 4.30 |
| CHEMBL2272808 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL2272811 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL2272810 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL2272812 | — | IC50 | = | 100000.0 | nM | 4.00 |