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Compound Detail

CHEMBL2272819

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N#C/N=C/N=C(\N)N/N=C/c1ccc(Cl)cc1

Basic Information

ChEMBL ID CHEMBL2272819
Phase Preclinical
Structure Type MOL
InChI Key JHGIPZUFWHVKAK-FZSIALSZSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

248.7
MW (Da)
1.09
ALogP
3
HBA
2
HBD
98.9
PSA (Ų)
0.36
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H9ClN6
MW 248.68
Aromatic Rings 1
Heavy Atoms 17
NP-Likeness -1.41

Activity Summary

IC50 1 meas. best 4.42

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Scenedesmus acutus
CHEMBL2367199
IC50 4.42 4.42 38018.9 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Scenedesmus acutus IC50 = 38018.94 nM 4.42 Phytotoxicity against Scenedesmus acutus assessed as inhibition of chlorophyll c... -

Literature References

PubMed DOI Target Context # Activities
- 10.1584/jpestics.20.119 Scenedesmus acutus 3

Data from ChEMBL 36 via Core Engine