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Assay Detail

CHEMBL3082041

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]EBOB from GABA receptor in Musca domestica (house fly) head P2 membrane after 70 min by liquid scintillation counting
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Musca domestica
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

GABA receptor subunit (CHEMBL3986)
Type SINGLE PROTEIN
Organism Musca domestica

Publication

Isocoumarin Derivative as a Novel GABA Receptor Ligand from Neosartorya quadricincta
Ozoe Y, Kuriyama T, Tachibana Y, Harimaya K, Takahashi N, Yaguchi T, Suzuki E, Imamura K, Oyama K
J Pestic Sci (2004) 29 : 328 -331
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.06 7.06

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1684587 1 7.06
CHEMBL2269235 DIHYDROISOCOUMARIN 1 7.06

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1684587 IC50 = 88.0 nM 7.06
CHEMBL2269235 DIHYDROISOCOUMARIN IC50 = 88.0 nM 7.06