GABA receptor subunit · SINGLE PROTEIN · Musca domestica
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As of 2026-09-14Protein identity stays anchored to UniProt Q75NA5. Use UniProt Q75NA5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q75NA5 as the stable identity anchor, then attach disease evidence before program review.
Gamma-aminobutyric acid receptor subunit beta
Review this target as GABA receptor subunit, mapped to UniProt Q75NA5. ChEMBL maps the protein component as Gamma-aminobutyric acid receptor subunit beta. Sequence length is 576 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats GABA receptor subunit as ChEMBL target CHEMBL3986, mapped to UniProt Q75NA5. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether GABA receptor subunit is the right protein anchor across sources, using UniProt Q75NA5 as the stable mapping.
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| Preferred Name | GABA receptor subunit |
| Target Type | SINGLE PROTEIN |
| Organism | Musca domestica |
| UniProt | Q75NA5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Gamma-aminobutyric acid receptor subunit beta |
| UniProt Accession | Q75NA5 |
| Component Type | Protein |
| Sequence Length | 576 aa |
Gamma-aminobutyric acid receptor subunit beta
Review this target as GABA receptor subunit, mapped to UniProt Q75NA5. ChEMBL maps the protein component as Gamma-aminobutyric acid receptor subunit beta. Sequence length is 576 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL101326 | 8.64 | IC50 | 2.3 | Preclinical |
| CHEMBL1890408 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL15891 | 7.96 | IC50 | 11.0 | Approved |
| CHEMBL206170 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL427379 | 7.13 | IC50 | 74.0 | Preclinical |
| CHEMBL377727 | 7.08 | IC50 | 83.0 | Preclinical |
| CHEMBL1684587 | 7.06 | IC50 | 88.0 | Preclinical |
| CHEMBL2269235 | 7.06 | IC50 | 88.0 | Preclinical |
| CHEMBL203278 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL206707 | 7.0 | IC50 | 100.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 8 | 14 | 6.8 |
| single protein format | 1 | 3 | 8.2 |