Compound Detail
CHEMBL101326
FIPRONIL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL101326 |
| Name | FIPRONIL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZOCSXAVNDGMNBV-UHFFFAOYSA-N |
11
Targets
13
Activities
2
Assay Types
0
PK Parameters
20
Publications
10
Known Names
Molecular Properties
437.1
MW (Da)
4.28
ALogP
5
HBA
1
HBD
90.7
PSA (Ų)
0.56
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Racemic |
Activity Summary
IC50 12 meas. best 8.64
EC50 1 meas. best 4.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| GABA-A receptor; anion channel CHEMBL2093872 | IC50 | 8.64 | 8.64 | 2.3 | 1 |
| GABA receptor subunit CHEMBL3986 | IC50 | 8.64 | 8.64 | 2.3 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 CHEMBL1847 | IC50 | 8.62 | 7.9067 | 2.4 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6/beta-3 CHEMBL3885578 | IC50 | 8.51 | 8.51 | 3.1 | 1 |
| GABA-A receptor; alpha-6/beta-3/gamma-2 CHEMBL2095190 | IC50 | 7.77 | 7.77 | 17.0 | 1 |
| GABA-A receptor alpha-1/beta-3 CHEMBL4106151 | IC50 | 7.55 | 7.55 | 28.0 | 1 |
| GABA-A receptor; alpha-1/beta-3/gamma-2 CHEMBL2094121 | IC50 | 7.48 | 7.48 | 33.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.6 | 5.6 | 2500.0 | 1 |
| GABA A receptor alpha-1/beta-1/gamma-2 CHEMBL2111392 | IC50 | 5.55 | 5.55 | 2800.0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1/ beta-1 CHEMBL3885570 | IC50 | 5.11 | 5.11 | 7700.0 | 1 |
| Nuclear receptor subfamily 1 group I member 2 CHEMBL3401 | EC50 | 4.82 | 4.82 | 15000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine