Assay Detail
Binding
CHEMBL683058
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]EBOB binding to drosophila GABA-A receptor (range 1-28)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Drosophila melanogaster |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Gamma-aminobutyric acid receptor subunit beta-3 (CHEMBL1847) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Fipronil-based photoaffinity probe for Drosophila and human beta 3 GABA receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.55 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL101326 | FIPRONIL | -1.0 | 1 | 7.55 |
| CHEMBL329306 | — | — | 1 | 7.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL101326 | FIPRONIL | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL329306 | — | IC50 | = | 28.0 | nM | 7.55 |