Assay Detail
Binding
CHEMBL3073472
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA beta3 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Gamma-aminobutyric acid receptor subunit beta-3 (CHEMBL1847) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Insecticide interactions with -aminobutyric acid and nicotinic receptors: predictive aspects of structural models
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.00 | 9.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1890408 | ALPHA-ENDOSULFAN | — | 1 | 9.33 |
| CHEMBL15891 | LINDANE | 4.0 | 1 | 9.05 |
| CHEMBL101326 | FIPRONIL | -1.0 | 1 | 8.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1890408 | ALPHA-ENDOSULFAN | IC50 | = | 0.47 | nM | 9.33 |
| CHEMBL15891 | LINDANE | IC50 | = | 0.9 | nM | 9.05 |
| CHEMBL101326 | FIPRONIL | IC50 | = | 2.4 | nM | 8.62 |