Assay Detail
Binding
CHEMBL3083633
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Bos taurus (beef) heart NAD1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
NADH-ubiquinone oxidoreductase chain 1 (CHEMBL4497) ↗| Type | SINGLE PROTEIN |
| Organism | Bos taurus |
Publication
Novel inhibitors of the mitochondrial respiratory chain: oximes and pyrrolines isolated from Penicillium brevicompactum and synthetic analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.36 | 8.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL429023 | ROTENONE | — | 1 | 8.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL429023 | ROTENONE | IC50 | = | 4.4 | nM | 8.36 |