NADH-ubiquinone oxidoreductase chain 1 · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P03887. Use UniProt P03887 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P03887 as the stable identity anchor, then attach disease evidence before program review.
NADH-ubiquinone oxidoreductase chain 1
Review this target as NADH-ubiquinone oxidoreductase chain 1, mapped to UniProt P03887. Sequence length is 318 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats NADH-ubiquinone oxidoreductase chain 1 as ChEMBL target CHEMBL4497, mapped to UniProt P03887. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | NADH-ubiquinone oxidoreductase chain 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P03887 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | NADH-ubiquinone oxidoreductase chain 1 |
| UniProt Accession | P03887 |
| Component Type | Protein |
| Sequence Length | 318 aa |
NADH-ubiquinone oxidoreductase chain 1
Review this target as NADH-ubiquinone oxidoreductase chain 1, mapped to UniProt P03887. Sequence length is 318 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1159657 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL445024 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2269127 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL320753 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL396297 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL1834283 | 8.54 | IC50 | 2.9 | Preclinical |
| CHEMBL272733 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL429023 | 8.36 | IC50 | 4.4 | Preclinical |
| CHEMBL2269126 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL2269125 | 7.77 | IC50 | 17.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 87 | 5.9 |