Assay Detail
Binding
CHEMBL3089086
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]NT(8 to 13) from human NTS2 receptor expressed in HEK293 cells
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of a (18)F-labeled diarylpyrazole glycoconjugate for the imaging of NTS1-positive tumors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.53 | 8.31 |
| Kd | 1 | 8.85 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL342252 | — | — | 1 | 8.85 |
| CHEMBL407196 | NEUROTENSIN | — | 1 | 8.31 |
| CHEMBL3086356 | — | — | 1 | 7.16 |
| CHEMBL3040381 | — | — | 1 | 7.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL342252 | — | Kd | = | 1.4 | nM | 8.85 |
| CHEMBL407196 | NEUROTENSIN | Ki | = | 4.9 | nM | 8.31 |
| CHEMBL3086356 | — | Ki | = | 69.0 | nM | 7.16 |
| CHEMBL3040381 | — | Ki | = | 74.0 | nM | 7.13 |