Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3090660

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human brain AChE using acetylthiocholine as substrate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Acetylcholinesterase (CHEMBL220)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Acetylcholinesterase inhibitors as Alzheimer therapy: from nerve toxins to neuroprotection.
Singh M, Kaur M, Kukreja H, Chugh R, Silakari O, Singh D.
Eur J Med Chem (2013) 70 : 165 -188
PubMed 24148993 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.39 8.39

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL195241 1 8.39

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL195241 IC50 = 4.1 nM 8.39