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Assay Detail

CHEMBL3090834

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of wild type mouse AChE expressed in HEK293 cells using ATCh as substrate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Cell Type HEK293
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Acetylcholinesterase (CHEMBL3198)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Divergent structure-activity relationships of structurally similar acetylcholinesterase inhibitors.
Andersson CD, Forsgren N, Akfur C, Allgardsson A, Berg L, Engdahl C, Qian W, Ekström F, Linusson A.
J Med Chem (2013) 56 : 7615 -7624
PubMed 23984975 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.96 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL345124 PROPIDIUM 1 5.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL345124 PROPIDIUM IC50 = 1100.0 nM 5.96