Assay Detail
Functional
CHEMBL3095697
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Antiproliferative activity against human 786-O cells assessed as ATP level after 72 hrs by CellTiter-Glo assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | 786-0 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New synthetic enediynes and their conjugates may provide effective treatment for cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 9.57 | 10.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3092453 | — | — | 1 | 10.24 |
| CHEMBL3092452 | — | — | 1 | 8.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3092453 | — | EC50 | = | 0.05803 | nM | 10.24 |
| CHEMBL3092452 | — | EC50 | = | 1.275 | nM | 8.89 |