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Assay Detail

CHEMBL3096539

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of pig/bovine heart myocardium PDE2 after 15 mins by scintillation proximity assay in presence of [3H]-cAMP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Myocardium
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

PDE2 inhibition: potential for the treatment of cognitive disorders.
Gomez L, Breitenbucher JG.
Bioorg Med Chem Lett (2013) 23 : 6522 -6527
PubMed 24189054 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.70 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL370962 1 8.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL370962 IC50 = 2.0 nM 8.70